A study on the impact of the absence of the NIP or NrpR gene on gene expression of Streptococcus salivarius K12 (SAL)

ABSTRACT: NIP and NrpR forms a pair for the transcriptional regulator in Streptococcus salivarius K12 (SAL). To explore the target genes regulated by the NIP-NrpR pair in Streptococcus salivarius K12 (SAL), we generated mutants in which the NIP or NrpR gene has been knocked down through complement recombination. Comparative transcriptome profiling of WT, ▲nrpR, and nip* mutant strains revealed that the sar BGC is the major regulatory target controlled by the NIP signaling pathway in SAL.

ORGANISM(S): Streptococcus salivarius K12

PROVIDER: GSE247581 | GEO | 2023/11/18

REPOSITORIES: GEO