Transcriptomics

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A single cell atlas of circulating immune cells involved in diabetic retinopathy


ABSTRACT: Circulating immune cells play a role in the pathophysiology of diabetic retinopathy (DR). Our study focused on examining the exact role of circulating immune cells in the development of DR. Single-cell RNA sequencing (scRNA-seq) techniques revealed unique differentially-expressed genes and pathways in circulating immune cells among non-diabetic retinopathy (NDR) patients and DR patients. These findings highlight the notable alterations in the immunophenotypes of circulating immune cells in patients with type 1 DR.

ORGANISM(S): Homo sapiens

PROVIDER: GSE248284 | GEO | 2024/02/14

REPOSITORIES: GEO

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