High and low cell density areas in posterior fossa ependymoma type A have a distinct transcriptome

ABSTRACT: Posterior fossa type A (PF-EPN-A, PFA) ependymoma are aggressive tumors that mainly affect children and have a poor prognosis. Histopathology shows significant intratumoral heterogeneity, ranging from loose tissue to often sharply demarcated, extremely cell dense tumor areas. Spatial transcriptomics of six cases allow for a comparison of the transcriptome of high and low cell density areas.

ORGANISM(S): Homo sapiens

PROVIDER: GSE249189 | GEO | 2024/01/31

REPOSITORIES: GEO