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The effects of JAK inhibition on SARS-CoV-2-induced kidney injury

ABSTRACT: Patients often present with kidney injury in COVID-19. Although severe COVID-19 cases are treated with baricitinib, a JAK inhibitor, the effects of baricitinib on the kidneys in COVID-19 are unclear. The authors examined the pharmacological effects of baricitinib on kidney injury using an in vivo murine COVID-19 model.

ORGANISM(S): Mus musculus

PROVIDER: GSE249303 | GEO | 2024/04/18

REPOSITORIES: GEO

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