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ChIP-seq assay for BRG1 in human SUP-B15 and Nalm-6 cell lines

ABSTRACT: Abstract: BRG1 is highly expressed in adult B-cells acute lymphoblastic leukemia and is associated with poor prognosis. High expression of BRG1 promotes the proliferation and resistance to apoptosis of B-ALL cells. BRG1 exerts these functions mainly through activation of the PI3K/AKT signaling pathway. In order to understand the specific regulatory mechanism, we used ChIP-seq to detect the DNA fragments bound by BRG1 in SUP-B15 and Nalm-6 cell lines.

ORGANISM(S): Homo sapiens

PROVIDER: GSE249559 | GEO | 2024/09/13

REPOSITORIES: GEO

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