Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

CeRNA-microarray reveals abnormal RNA of tuberculosis in PBMC

ABSTRACT: RNAs can provide abundant pathological information regarding etiology and could include candidate biomarkers for diagnosis of tuberculosis.Our study focused on RNA expression profiles. The purpose of our study is characterized the RNA profiles of tuberculosis patients and identified significant lncRNAs, circRNA and mRNA associated with tuberculosis as diagnostic biomarkers and treatment target.

ORGANISM(S): Homo sapiens

PROVIDER: GSE249824 | GEO | 2024/02/28

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

ceRNA-microarray reveals abnormal RNA of tuberculosis in PBMC

Project description:ceRNA-microarray reveals abnormal RNA of tuberculosis in PBMC

| PRJNA1050794 | ENA

miRNA expression profiles of PBMC from Normal Heatlh and Tuberculosis Patients

Project description:To analysis the miRNA expression profiles of PBMC from Normal Heatlh and Tuberculosis Patients

2018-09-06 | GSE119494 | GEO

Differential expression Profiles of microRNAs in PBMC specimen from tuberculosis patients and normal volunteers

Project description:Purpose: To investigate the role and mechanism of microRNAs in tuberculosis. Methods: microRNAs sequencing were performed to screen differential expressed microRNAs in PBMC specimen between tuberculosis patients and normal volunteers. Results: A total of 1560 distinct microRNAs were identified in these samples, and 788 of these microRNAs were upregulated and 772 microRNAs were downregulated. Overall design: Tuberculosis differential expression Profiles of microRNAs in PBMC were generated by high throughput sequencing, using Illumina Hiseq2000/2500.

2022-07-03 | GSE207244 | GEO

Dysregulated circRNAs in plasma from active tuberculosis patients

Project description:Role of circRNAs in active tuberculosis (TB) remains unknown. The present study was aimed to determine plasma circRNA expression profile in active TB patients to identify potential biomarker by circRNA microarrays.

2018-07-06 | GSE106953 | GEO

RNAseq Mycobacterium Tuberculosis

Project description:We analyzed the genes expressed, or the transcriptome, of bacilli (Mycobacterium tuberculosis) growing in fatty acids as sole carbon source. Using new technologies to massively sequence of RNA molecules we identified a group of genes that provides novel insight regarding the metabolic pathways and transcriptional regulation of latent M. Tuberculosis.

2013-06-13 | GSE47863 | GEO

RNAseq Mycobacterium Tuberculosis

2013-06-13 | E-GEOD-47863 | biostudies-arrayexpress

A blood RNA signature for tuberculosis disease risk in household contact study - GC6 cohort.

Project description:Identification of blood biomarkers that prospectively predict progression of Mycobacterium tuberculosis infection to tuberculosis disease might lead to interventions that combat the tuberculosis epidemic in the context of house hold contacts.

2018-04-10 | GSE94438 | GEO

Small RNAs in anti-tuberculosis drug-induced liver injury

Project description:The antimicrobials isoniazid and pyrazinamide, used for the treatment of tuberculosis are known to cause drug-induced liver injury in humans. This limits the effectiveness of tuberculosis treatment, resulting in incomplete cure, relapse and the development of antimicrobial resistance. MicroRNAs are known to be good biomarkers of disease, with the microRNA miR-122 being diagnostic for liver injury. In this study zebrafish larvae were exposed to the anti-tuberculosis drugs isoniazid and pyrazinamide at concentrations which demonstrated liver injury by microscopy and histology. The aim of this study is to understand small RNA changes occurring in anti-tuberculosis drug-induced liver injury and to attempt to identify novel microRNA biomarkers of liver injury.

2023-12-25 | GSE146260 | GEO

Defining Gene Signatures for Protective Immunity to Tuberculosis in the Rhesus Macaque Model

Project description:Gene expression profiles in PPD-stimulated and unstimulated peripheral blood mononuclear cells isolated from rhesus macaques before and after M. tuberculosis challenge were compared in animals able to control TB infection and those that developed TB disease in order to identify potential correlates of protection and/or biomarkers of disease.

2018-12-16 | E-MTAB-7558 | biostudies-arrayexpress

Identification of differential circRNA expression profiles in human macrophages induced by viru-lent and avirulent Mycobacterium tuberculosis strains

Project description:Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis (M.tb) infection, remains a leading cause of morbidity and mortality world-wide. Circular RNAs are non-coding RNAs with diverse functions. However, most M.tb related circRNAs remain undiscovered. We used circRNA-seq technology to sequence the THP-1 cells infected with virulent and avirulent M.tb strains for 12 h.

2024-04-10 | GSE248244 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data