Genomics

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Drosophila zinc finger proteins CG9609, AEF1 and CG10543 are colocalized with SAGA, SWI/SNF and ORC complexes on gene promoters and involved in transcription regulation


ABSTRACT: We purified the DUB module of the Drosophila SAGA complex and found that a number of zinc proteins interact with it, including CG9609, Aef1 and CG10543. A genome-wide study showed that CG9609, Aef1 and CG10543 proteins are localized predominantly on the promoters of active genes. The binding sites of these proteins colocalize with the SAGA, dSWI/SNF and ORC complexes. It has been shown that CG9609, Aef1 and CG10543 proteins are involved in transcription regulation.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE250183 | GEO | 2023/12/20

REPOSITORIES: GEO

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