Transcriptomics

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Expression data from CD19-positive splenic B cells isolated from 1-month old ID4+/-TCL1-tg and ID4+/+TCL1-tg mice


ABSTRACT: The function of ID4 in CLL development was studied in vivo using TCL1 transgenic mouse model that develop leukemia similar to human CLL. TCL1 mice with ID4 single knockout gene have accelerated CLL progression. Results from the animal study suggest ID4 as a tumor suppressor gene that might regulate cell proliferation and apoptosis in B lymphocytes.

ORGANISM(S): Mus musculus

PROVIDER: GSE25100 | GEO | 2010/11/04

SECONDARY ACCESSION(S): PRJNA134723

REPOSITORIES: GEO

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