Gene expression data from Pseudomonas aeruginosa strains isolated from cystic fibrosis lung infections
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ABSTRACT: Pseudomonas aeruginosa is a common pathogen in the lungs of the cystic fibrosis patients. As infection develops the organism progressively adapts to its environment and its mode of pathogenesis alters, frequently including the loss of quorum sensing regulated virulence factors. We used microarrays to detail differences between two P. aeruginosa isolates from CF patients, one of which (UUPA38) exhibited an active quorum sensing system (QS+) typical of early acute infection while the other (UUPA85) was QS-compromised (QS-) typical of chronic CF-adapted infection.
ORGANISM(S): Pseudomonas aeruginosa
PROVIDER: GSE25128 | GEO | 2010/11/04
SECONDARY ACCESSION(S): PRJNA142761
REPOSITORIES: GEO
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