NF1 deficiency drives metabolic reprogramming in ER+ breast cancer
Ontology highlight
ABSTRACT: NF1 deficiency drives metabolic reprogramming in ER+ breast cancer. This reprogramming is characterized by oxidative ATP constraints, glutamine TCA influx, and lipid pool expansion, and these metabolic changes introduce novel metabolic-to-targeted inhibitor synergies.
ORGANISM(S): Homo sapiens
PROVIDER: GSE251692 | GEO | 2023/12/25
REPOSITORIES: GEO
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