Transcriptomics

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TTA/TDP Mice Expression Array


ABSTRACT: Transgenic (Tg) mice expressing nuclear or cytoplasmic human TDP-43 were generated. Tg mice had motor spasticity and forebrain neurodegeneration. Human TDP-43 reduced mouse TDP-43 in nuclei of affected neurons. Tg mice showed alterations in transcripts related to chromatin assembly.

ORGANISM(S): Mus musculus

PROVIDER: GSE25182 | GEO | 2010/11/10

SECONDARY ACCESSION(S): PRJNA134527

REPOSITORIES: GEO

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