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Spatial transcriptome analysis unveils an innate immune activation signature of acute T cell-mediated rejection in kidney transplants


ABSTRACT: To unveil the molecular mechanisms underlying TCMR, we utilized spatial transcriptomics on post-transplant TCMR and non-TCMR patients. Contrary to the prevailing T cell-centric view, our findings reveal uniform inflammatory responses across glomerular and tubulointerstitial regions in TCMR.

ORGANISM(S): Homo sapiens

PROVIDER: GSE252137 | GEO | 2024/02/16

REPOSITORIES: GEO

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