Transcriptomics

Dataset Information

0

The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates MYC as a Hypertrophic Regulator


ABSTRACT: Molecular control of recovery after exercise in muscle is temporally dynamic. A time course of biopsies around resistance exercise (RE) combined with -omics is necessary to better comprehend the molecular choreography of skeletal muscle adaptation in humans. We collected vastus lateralis biopsies before and 30 minutes, 3-, 8-, and 24 hours after acute RE. RNA-sequencing defined the transcriptome and a time-point matched biopsy only group were controls. DNA methylomics and computational approaches complimented the transcriptome data. Moreover, we tested whether cyclic transient overexpression of transcription factor MYC for 4 weeks were sufficient to induce skeletal muscle hypertrophy in female mice.

ORGANISM(S): Homo sapiens

PROVIDER: GSE252357 | GEO | 2024/04/17

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2020-03-26 | PXD017805 | Pride
2013-11-15 | E-GEOD-45426 | biostudies-arrayexpress
2012-02-21 | GSE28422 | GEO
2022-08-25 | PXD034908 | Pride
2004-10-14 | GSE1832 | GEO
2013-11-15 | GSE45426 | GEO
2022-03-01 | E-MTAB-11282 | biostudies-arrayexpress
2006-02-17 | E-GEOD-4247 | biostudies-arrayexpress
2014-09-01 | E-GEOD-27543 | biostudies-arrayexpress
2018-09-10 | GSE106865 | GEO