Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single-cell RNA-sequencing from stroma in a mouse submandibular salivary gland following 14-day ligation or mock surgery

ABSTRACT: The submandibular salivary gland stroma makes up only a small portion of the total salivary gland and the stromal response to salivary gland injury has been understudied. We used single-cell RNA-sequencing (scRNAseq) to analyze which cell types are present in ductal ligated and mock surgery salivary glands, how the cell type abundance is altered during injury, and how the transcriptome of those cells is being altered. This will allow us to examine which cell types are important contributors to recovery from salivary gland ductal ligation injury.

ORGANISM(S): Mus musculus

PROVIDER: GSE253916 | GEO | 2024/01/23

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Single-cell RNA-sequencing from stroma in a mouse submandibular salivary gland 14 days after ligation or mock surgery

Project description:The submandibular salivary gland stroma makes up only a small portion of the total salivary gland and the stromal response to salivary gland injury has been understudied. We used single-cell RNA-sequencing (scRNAseq) to analyze which cell types are present in both control and ligated samples, how the cell type abundance is altered following injury, and how the transcriptome of those cells is being altered. This will allow us to examine which cell types are important contributors to fibrosis induced by salivary gland ductal ligation injury.

2023-03-29 | GSE226640 | GEO

Single-cell RNA-sequencing from stroma in a mouse submandibular salivary gland following 5-day deligation or control homeostatic

Project description:The submandibular salivary gland stroma makes up only a small portion of the total salivary gland and the stromal response to salivary gland injury has been understudied. We used single-cell RNA-sequencing (scRNAseq) to analyze which cell types are present in deligated and homeostatic salivary glands, how the cell type abundance is altered during regeneration, and how the transcriptome of those cells is being altered. This will allow us to examine which cell types are important contributors torecovery from salivary gland ductal ligation injury.

2023-07-01 | GSE235677 | GEO

Genome-wide expression analysis of submandibular salivary gland tumours of Smgb-Tag mice

Project description:To reveal novel molecular factors behind the development of salivary gland cancer, we performed gene expression analyses from Smgb-Tag mouse salivary gland samples. The overall purpose was to apply these results for clinical use to find new approaches for both possible therapeutic targets and more accurate diagnostic tools in identification of salivary gland cancers. Smgb-Tag mouse strain, in which salivary neoplasms arise through a dysplastic phase in submandibular glands, was investigated using genome-wide microarray expression analysis, Ingenuity pathway analysis, RT-PCR, and immunohistochemistry. 3 normal, 3 dysplastic, and 3 adenocarcinomatous submandibular gland tumours of Smgb-Tag mice.

2014-09-30 | E-GEOD-61868 | biostudies-arrayexpress

Transcription profiling by array of submandibular salivary glands from PAP knockout and wild type mice

Project description:Prostatic acid phosphatase is the main acid phosphatase in mouse submandibular salivary gland

2014-04-15 | E-MTAB-2099 | biostudies-arrayexpress

Genome-wide expression analysis of submandibular salivary gland tumours of Smgb-Tag mice

2014-09-30 | GSE61868 | GEO

Functional characterization and genomic studies of a novel murine submandibular gland epithelial cell line.

Project description:Gene expression analysis of spontenously immortalized mouse submandibular salivary gland epithelial cells grown in culture at different passages and in different media conditions

2018-02-01 | GSE98250 | GEO

Expression data from human submandibular gland cell lines

Project description:The immortalized normal human salivary gland ductal cells (NS-SV-DC) and acinar cells (NS-SV-AC) had characteristic morphologic differences, and useful for organizing knowledge of bio-functional mechanisms of human salivary gland.

2020-03-14 | GSE116724 | GEO

microRNAs expression of human submandibular gland cell lines

Project description:The immortalized normal human salivary gland ductal cells (NS-SV-DC) and acinar cells (NS-SV-AC) have characteristic morphologic differences and useful for organizing knowledge of bio-functional mechanisms of human salivary gland.

2018-07-10 | GSE116828 | GEO

Single-cell and Bulk Transcriptomics of the Human Submandibular Gland Reveals Conserved Factors and Pathways [Bulk RNA-seq]

Project description:We performed bulk RNA-sequencing analysis of human submandibular gland samples and then compared to expression of multiple human tissues in order to identify a salivary gland gene signature.

2023-02-08 | GSE199208 | GEO

Gene expression profiles for murine submandibular gland stem cells

Project description:To compare the gene expression profile of submandibular gland stem cells to submandibular gland epithelia, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the differential expression in the stem cells and the non-stem cell epithelia. Murine submandibular gland stem cells and non-stem cell epithelia are sorted through FACS

2014-07-01 | E-GEOD-46672 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data