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The effects of HSP60 chaperone deficiency on zebrafish larvae

ABSTRACT: To understand the effects of Hsp60 deficiency in developing vertebrates, we generated CRISPR/Cas9-mediated hspd1 knockout zebrafish lines by targeting exon 2 to induce a frameshift mutation. We selected an allele with a 56 base pair deletion inducing a frameshift mutation leading to loss of protein functions. We examined the transcriptome changes in zebrafish larvae at 5 dpf .

ORGANISM(S): Danio rerio

PROVIDER: GSE254091 | GEO | 2024/09/27

REPOSITORIES: GEO

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The proteomics effects of HSP60 chaperone deficiency in zebrafish larvae

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