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RNA sequencing in the Kasumi-1 cell line transfected with PHF19 shRNA or scrambled control shRNA

ABSTRACT: To investigate the fuctional role of PHF19 in the regulation of cell cycle progression in t(8;21) AML, we established Kasumi-1 cell line in which PHF19 gene has been knocked down by shRNA. We then performed bulk RNA sequencing to analyze the changes of gene expression profiling in the PHF19 knockdown cells as compared with the scrambled control cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE254526 | GEO | 2024/02/05

REPOSITORIES: GEO

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Detect accessible chromatin using ATAC sequencing in the Kasumi-1 cell line transfected with PHF19 shRNA or scrambled control shRNA

Project description:To investigate the function of PHF19 in the regulation of chromatin accessibility in t(8;21) AML, we established Kasumi-1 cell line in which PHF19 gene has been knocked down by shRNA. We then performed chromatin accessibility analysis using data obtained from ATAC-seq of the PHF19 knockdown cells and the scrambled control cells.

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PHF19 shRNA or scrambled control shRNA

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PHF19 shRNA or scrambled control shRNA

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