Transcriptomics

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Gene expression data in Bone Marrow Derived Dendritic Cells (BMDC) following nanoemulsion adjuvant exposure


ABSTRACT: Antigen uptake, processing and presentation by dendritic cells are regulated by complex intra- and inter-cellular signalling events. Typical vaccine adjuvants lead to the transcription of pro-inflammatory cytokines and chemokines which relate to immune induction. We used microarrays to detail the global expression of genes in BMDC underlying emulsion internalization and DC activation with a non-inflammatory nanoemulsion adjuvant.

ORGANISM(S): Mus musculus

PROVIDER: GSE25485 | GEO | 2010/11/18

SECONDARY ACCESSION(S): PRJNA142603

REPOSITORIES: GEO

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