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Reanalysis of white and brite adipocyte ChIP-Seq of PPARG and MED1 in the hg38 genome

ABSTRACT: To compare the binding of PPARG and MED1 at the TSSes of differentially expressed isoforms in white and brite (also known as beige) adipocytes, data from GSE59703 (Loft et al., 2015) was reanalysed on the hg38 genome. We find that a large majority of the splice variants arise from differential TSS usage, with beige-specific TSSs being enriched for PPARγ and MED1 binding compared to white-specific TSSs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE256261 | GEO | 2024/05/14

REPOSITORIES: GEO

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