Genomics

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ChIP–seq on periosteal cells derived from the pre-invasive group using antibodies to acetylated histone H3 Lys27 (H3K27ac), H3K4me3 and HIF-1α


ABSTRACT: To test whether HIF-1a can directly induce Timp1 expression in periosteal cells at the pre-invasive stage of head and neck squamous cell carcinoma (HNSCC), we performed Chromatin immunoprecipitation followed by sequencing (ChIP–seq) on periosteal cells derived from the pre-invasive stage of a mouse HNSCC bone invasion model by using antibodies to acetylated histone H3 Lys27 (H3K27ac), H3K4me3 and HIF-1α.

ORGANISM(S): Mus musculus

PROVIDER: GSE256307 | GEO | 2024/06/17

REPOSITORIES: GEO

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