LINC00894 promotes neuronal survival by regulating the expression of ATF3.

ABSTRACT: There is evidence suggesting that LINC00894 may have a biological role in the brain, but the exact function of this gene remains largely unknown. In this study, we discovered that LINC00894 regulates neuronal cell apoptosis. Using RNA-seq, we identified a gene cluster regulated by LINC00894 in M17 neuroblast cell line, and qRT-PCR analysis demonstrated that LINC00894 may affect cell viability by modulating the expression of ATF3 in neuronal cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE256536 | GEO | 2024/03/03

REPOSITORIES: GEO