Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Phase separation of N-myc differentially modulates the transcriptom

ABSTRACT: SPARK-ON tag does not perturb the core transcriptional function of n-Myc.~2260 DEGs with ≥ 1.5-fold change in transcript level, including ~1270~6900 DEGs with ≥ 1.5-fold change in transcript level, including ~3100 up-regulated. By compare n-Myc condensed phase and dilute phase, 99 DEGs that were differentially expressed with ≥ 1.5-fold change. in transcript levels, including 88 up-regulated genes and 11 down-regulated genes and ~3800 down-regulated genes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE259300 | GEO | 2024/02/28

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Phase separation of YAP-MAML2 differentially regulates the transcriptome

Project description:SPARK-OFF tag does not perturb the core transcriptional function of YAP-MAML2.~2260 DEGs with ≥ 1.5-fold change in transcript level, including ~1270 up-regulated genes and ~990 down-regulated genes can be identified from YAP-MAML2 overexpression HEK293T cells.We identified 88 DEGs (p-value < 0.01, |Log2FC| ≥ 0.58, FDR < 0.1) that are regulated by YAP-MAML2 phase separation with ≥ 1.5-fold change in transcript levels, including 44 up-regulated genes and 44 down-regulated genes

2024-01-23 | GSE253678 | GEO

RNA-Seq from zmknl1 and WT kernels at 14 DAP (day after pollination) with each two independent biological replicates

Project description:To further understand the basis of the phenotypic defects in the zmknl1 mutant, we performed RNA-Seq from zmknl1 and WT kernels at 14 DAP with each two independent biological replicates. Totally 555 significantly differentially expressed genes (DEGs) were identified according to these RNA-Seq data (q-value <0.05, log2(fold change) >= 1.5), with 317 down- and 238 up-regulated genes.

2019-12-21 | GSE124245 | GEO

Gene expression profiling of MDA-MB-468 cells following p53-R273H mutant knock-down

Project description:A total of 58 genes were up-regulated (> 1.5 fold-change) while 117 genes were down-regulated

2016-06-30 | GSE65967 | GEO

Drosophila the 3rd instar larvae testis: Control vs. Wolbachia-infected

Project description:Transcriptional profiling of Drosophila melanogaster larval testes with and without the wMel strain of Wolbachia and found that 296 genes had at least a 1.5 fold change [q-value (%)<5%] in transcript levels, with 167 genes up-regulated and 129 genes down-regulated when comparing Wolbachia-infected flies to uninfected ones. Differential expression of genes related to metabolism, immunity, reproduction and other functions were observed.

2012-07-01 | GSE32601 | GEO

Bovine blood gamma/delta T cell stimulation study

Project description:Blood gamma/delta T cells were purfiied from holstein calves less than six months old. Blood from 4 individual calves were pooled and gamma/delta T cells were purified by immunomagnetic separation, rested in RPMI medium for 12h, and underwent ConA & hIL-2 stimulation. Total RNAs were extracted by using Trizol reagents. 15 ug of total RNA was used for cDNA synthesis and microarray hybridization. Table 1: regulated genes These genes were identified, in GeneSpring software, via filtering of genes with relative expression ratio of 1.5 and over or 0.667 or below, equivalent to up- and down-regulation by fold change 1.5 or more, in both experiments. Table 2: down-regulated genes These genes were identified, in GeneSpring software, via filtering of genes with relative expression ratio of 0.667 or below, equivalent to down-regulation by fold change 1.5 or more, in both experiments. The avergae fold change was then converted to negative value. Gene annotation was performed by using GeneSpring's "Build Simplified Ontology" constructor. Table 3: up-regulated genes These genes were identified, in GeneSpring software, via filtering of genes with relative expression ratio of 1.5 or over, equivalent to up-regulation by fold change 1.5 or more, in both samples. Gene annotation was performed by using GeneSpring's "Build Simplified Ontology" constructor. Keywords: other

2004-10-28 | GSE1870 | GEO

Comparison of gene expression profiles between MC3T3-E1 without osteoblastic induction and with 14 days of ostoblastic induction

Project description:Microarray study revealed 1324 genes that were up-regulated and 1550 genes that were down-regulated more than 1.5 fold change (corrected p<0.05) in MC3T3-E1-derived-mature Osteoblasts compared to control MC3T3-E1.

2019-04-21 | GSE46400 | GEO

The Jejunum Mucosa of Female Black-boned Chickens: Control vs. Heat-stressed Treatment

Project description:Transcriptional profiling of the jejunum mucosa with 1.5 fold-change reporter genes in comparing control black-boned chickens under normal temperature (NT) conditon with heat-stress treated black-boned chickens under high temperature (HT) condition. Goal was to determine the differentially expressed genes (DEGs) in co-family black-boned chickens exposure to heat stress based on global chicken gene expression.

2015-07-28 | GSE71352 | GEO

Transcriptome analysis using RNA sequencing conducted for wild type (Col-0) and a stable transgenic line with ectopic expression of AT3G11290 (35S:HIN1) under control conditions and after 96 hours at moderate low water potential stress (-0.7 MPa)

Project description:RNA sequencing was used to identify alternative splicing events and differentially expressed genes (DEG) in 35S:HIN1 stable transgenic line compared to Col-0 wild type. Two treatments were analyzed for each genotype: unstressed control and a 96 hours moderate severity low water potential (-0.7 MPa) treatment. RNA sequencing analysis found that overexpression of HIN1 in unstressed plants was sufficient to duplicate the effects of stress on nearly 40% of the genes where intron retention was normally suppressed by stress in wild type. Differentially expressed genes (DEGs) were also analyzed (P < 0.05 and fold change ≥ 1.5 used as cut off values for DEGs). Differentially expressed genes in 35S:HIN1has limited overlap of DEGs between 35S:HIN1and wild type. This indicated that HIN1 plays a lesser role in stress-regulated gene expression than in splicing regulation.

2019-10-01 | GSE127805 | GEO

Bovine blood gamma/delta T cell stimulation study

2010-06-05 | E-GEOD-1870 | biostudies-arrayexpress

search for downstream target genes of HTG3 based on RNA seq data

Project description:With the threshold of absolute value of log2 (Fold Change) ≥1 and P < 0.05, 4122 and 4100 differentially expressed genes (DEGs) were up-regulated and down-regulated, respectively by HS in ZH11; 4725 genes(H-DEGs) were up or down-regulated in the htg3 mutant under normal or stress conditions; Among the H-DEGs, 1025 and 947 genes were up- and down-regulated, respectively, by HS in ZH11.

2022-02-28 | GSE197401 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data