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Genome-wide identification and analysis of gene expression in brains of mice infected with FJDRV, a street rabies virus with high virulence, and ERA, a laboratory-adapted virus with lower virulence

ABSTRACT: Host-virus interaction was analyzed at gene expression level. The hypothesis tested in the present study was that rabies virus (RABV) infection affects the gene expression in brains of mice and RAB with different virulence induce distinct expression pattern in host. Results provide important information that RABV infection led to alteration of gene expression in brains of mice and FJDRV, a street rabies virus with highly virulence isolated from brain of rabid dog in Fujian provice of China, or ERA, a laboratory-adapted rabies virus with lower virulence induced different expression pattern, including immune-related and cellular signaling-related genes.

ORGANISM(S): Mus musculus

PROVIDER: GSE26270 | GEO | 2012/10/10

SECONDARY ACCESSION(S): PRJNA142313

REPOSITORIES: GEO

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Genome-wide identification and analysis of microRNA expression in brains of mice infected with FJDRV, a street rabies virus with high virulence, and ERA, a laboratory-adapted virus with lower virulence

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