Transcriptomics

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Genomic positioning in LBR and Lamin A K562 knockout cells


ABSTRACT: To probe the functional consequences of nuclear lamina genome association, we made LMNA, LBR, and double LMNA/LBR K562 knockout lines. We first examined the genome interaction changes with nulcear lamina using LMNB1 DamID seq and further assessed the functional consequences of these changes using RNA-seq and repli-seq.

ORGANISM(S): Homo sapiens

PROVIDER: GSE263012 | GEO | 2024/04/04

REPOSITORIES: GEO

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