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Stress granule assembly impairs macrophage efferocytosis [MeRIP-seq]

ABSTRACT: Stress granules (SGs) assembly in response to various stress, has been demonstrated in the regulation of anti-viral immune response and tumor progression. However, lack of evidence to illustrate the relation between SGs formation and allergic diseases. Using m7G meRIP-seq for CDS region of mRNA in macrophages, m7G modification of Lrp1 mRNA is defined.

ORGANISM(S): Mus musculus

PROVIDER: GSE263851 | GEO | 2024/05/01

REPOSITORIES: GEO

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Stress granule assembly impairs macrophage efferocytosis [SG RNA-seq]

Project description:Stress granules (SGs) assembly in response to various stress, has been demonstrated in the regulation of anti-viral immune response and tumor progression. However, lack of evidence to illustrate the relation between SGs formation and allergic diseases. Applying RNA-seq in total RNA and SGs of primary macrophages, SG-specific expressed genes were defined.

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