Transcriptomics

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Large-scale transcript variants dictate neoepitopes for cancer immunotherapy


ABSTRACT: Neoantigen tumor vaccines have shown promising anti-tumor efficacy in early clinical trials. However, the underlying mechanism regarding response or resistance to this treatment remains unclear. Therefore, further studies using advanced technologies such as single-cell RNA sequencing (scRNA-seq) were performed to reveal significant changes in tumor microenvironment after vaccination.

ORGANISM(S): Mus musculus

PROVIDER: GSE264082 | GEO | 2024/04/21

REPOSITORIES: GEO

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