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Sarcoidosis miRNA Blood Profiles

ABSTRACT: This project analyzes peripheral blood profiles of Sarcoidosis patients. Since miRNAs are known to be valuable diagnostic markers we asked whether respective patterns of patients can be detected in peripheral blood samples rather than in biopsies. The project aimed at an impoved understanding of complex profiles rather than single markers. Thus, a high-throughput technique was necessary, profiling all known miRNAs integratively.

ORGANISM(S): Homo sapiens

PROVIDER: GSE26409 | GEO | 2013/01/01

SECONDARY ACCESSION(S): PRJNA136869

REPOSITORIES: GEO

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Sarcoidosis miRNA Blood Profiles

Project description:This project analyzes peripheral blood profiles of Sarcoidosis patients. Since miRNAs are known to be valuable diagnostic markers we asked whether respective patterns of patients can be detected in peripheral blood samples rather than in biopsies. The project aimed at an impoved understanding of complex profiles rather than single markers. Thus, a high-throughput technique was necessary, profiling all known miRNAs integratively. n = 55 normal controls and n = 45 Sarcoidosis samples have been screened for the complete miRNA repertoire. Please note that each miRNA has been measured in seven replicates and the median of the replica has been computed.

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