Project description:CD73ko and control mice were subjected to transient middle cerebral artery occlusion (tMCAO) for 50min or subjected to equally long sham surgery. Whole brain RNA was isolated and analyzed with the NanoString nCounter® mouse glial profiling panel.
Project description:Gene expression of HLADR+ve blood monocytes from healthy control and patients with ARDS assayed on NanoString nCounter Human Myeloid Innate Immunity Panel panel. Nanostring expression data
Project description:Radical prostatectomy remains one of the more widely-used treatment options for men with prostate cancer. However, few molecular biomarkers have been established to predict patients who are at high risk of biochemical failure. To our knowledge, this is the first such report on miRNA profiling in radical prostatectomy tissue using Nanostring. In addition, this is the first report to look at the prognostic value of miRNAs in the setting of biochemical failure and salvage radiation therapy post-radical prostatectomy. RNA was extracted from tumor-enriched 1mm cores from 43 radical prostatectomy paraffin tissue blocks. 800 miRNAs were profiled using the NanoString nCounter human miRNA assay. mirNAs were then correlated to clinical outcomes.