Methylomic profiling of melanoma tissues from patients prior to immune checkpoint blockade to identify predictors of response or resistance

ABSTRACT: Genome wide DNA methylation profiling of formalin-fixed paraffin-embedded (FFPE) melanoma tissue samples from patients prior to treatment with anti-PD1 immune checkpoint inhibitor therapy. The MethylationEPIC v1.0 BeadChip array was used to obtain DNA methylation profiles across approximately 850,000 CpGs in bisulfite treated DNAs extracted from formalin-fixed paraffin embedded melanoma tissues prior to treatment with anti-PD1 immune checkpoint inhibitor therapy.

ORGANISM(S): Homo sapiens

PROVIDER: GSE264158 | GEO | 2025/04/15

REPOSITORIES: GEO