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Wildtype and PALS1 knockout MDCKII cells grown under non-confluent and in 3D cyst cultures

ABSTRACT: To investigate how gradual differences in the tight junction formation could be linked to an altered gene expression, wildtype and PALS1 knockout cell lines were grown under non-confluent and in 3D cyst cultures. After preparation of the mRNA samples, mRNASeq was performed. Normalized gene expression data was then was analyzed for differentially expressed genes, and GO-Term enrichment studies were used to elucidate involved pathways.

ORGANISM(S): Canis lupus familiaris

PROVIDER: GSE264311 | GEO | 2024/11/30

REPOSITORIES: GEO

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