Transcriptomics

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U1 cells stimulated with the TLR8 agonist 3M-002 at 10 microM show a prominent activation of TLR-dependent genes as assessed by "Human toll-like Receptor PCR array pathway" over time


ABSTRACT: We investigated the effects of the TLR8 agonist 3M-002 on latently HIV infected U1 cells. We found a prominent upregulation of TLR-dependent genes. Notably, the TLR8 agonist resulted in a marked activation of HIV.

ORGANISM(S): Homo sapiens

PROVIDER: GSE26469 | GEO | 2011/01/11

SECONDARY ACCESSION(S): PRJNA136541

REPOSITORIES: GEO

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