Transcriptomics

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The prior probability can derive the variety in the interpretation of p-value


ABSTRACT: In contrast to its common definition and calculating process, interpretations of p-value differ among statisticians. Since p-value is the basis of various methodologies, this divergence has led to distinct test methodologies as well as various opinions for evaluating test results, producing a chaotic situation. Here the origin of the divergence is found in the differences among Pr(H0 = true), which gives a prior probability in the definition of p-values. Effects of differences in the prior probability on the character of p-values are investigated by comparing microarray data and random numbers as subjects. The summarized levels the genes are presented in the matrix files (linked below as supplementary files). Student t-test was applied between the two groups (0h and 14d): p-values presented in the matrix files.

ORGANISM(S): Mus musculus

PROVIDER: GSE26498 | GEO | 2011/01/12

SECONDARY ACCESSION(S): PRJNA136723

REPOSITORIES: GEO

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