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Single-cell profiling of penta- and tetradactyl mouse limb buds identifies early mesenchymal progenitors required to specify digit numbers and asymmetry

ABSTRACT: Developing limb cells are heterogeneous. We used single cell RNA sequencing to compare a wildtype limb to two different Grem1 tetradactyl mutants at E10.75 and found differences in populations.

ORGANISM(S): Mus musculus

PROVIDER: GSE267005 | GEO | 2025/01/10

REPOSITORIES: GEO

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Single-cell profiling of penta- and tetradactyl mouse limb buds identifies early mesenchymal progenitors required to specify digit numbers and asymmetry

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Single-cell profiling of penta- and tetradactyl mouse limb buds identifies mesenchymal progenitors controlling digit numbers and identities.

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