Transcriptomics

Dataset Information

0

Genes associated with mitogen-activated protein kinase activity in pancreatic cancer cells


ABSTRACT: We performed a transcriptome analysis to determine what genes were altered in expression when U0126, MAP2K inhibitor, was administered to cells of human pancreatic cancer cell lines. Five genes including ETV5, ETV4, COL13A1, HIST1H4L/H4C13, and WDR62 were found to be particularly downregulated by the inhibition of MAPK pathway, meaning that these genes were preferentially upregulated by the active MAPK. The expression of ETV5 was most modulated, suggesting that ETV5 is strongly associated with the MAPK activity and may play a role in human pancreatic cancer.

ORGANISM(S): Homo sapiens

PROVIDER: GSE268817 | GEO | 2024/06/05

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2023-01-01 | GSE216710 | GEO
2022-07-02 | GSE207179 | GEO
2009-10-02 | E-GEOD-18267 | biostudies-arrayexpress
2012-02-01 | E-GEOD-33997 | biostudies-arrayexpress
2015-09-13 | GSE47225 | GEO
2016-04-28 | GSE80734 | GEO
2011-03-24 | E-GEOD-21209 | biostudies-arrayexpress
2011-03-25 | GSE21209 | GEO
2017-04-10 | GSE89618 | GEO
2012-02-01 | GSE33997 | GEO