Transcriptomics

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Impact of Chronic Olanzapine Administration on Gene Expression in the Mouse Lateral Septum


ABSTRACT: To explore the effects of long-term olanzapine treatment on gene expression in the lateral septum of female mice, we conducted a study using female C57BL/6 mice fed with olanzapine-supplemented chow for 12 weeks. The treated mice exhibited significant weight gain and lipid alterations compared to the control group. Subsequently, RNA-seq was performed on the lateral septum brain regions of both the treated and control mice, followed by gene expression profiling to analyze the data.

ORGANISM(S): Mus musculus

PROVIDER: GSE268867 | GEO | 2024/07/03

REPOSITORIES: GEO

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