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Transcriptional analysis of ocular tissue from MCMV infected neonatal mice treated with CXCR3 blocking antibody

ABSTRACT: Congenital CMV is the leading cause of congenital infections leading to several different neurological complications including ocular pathology. MCMV infeciton of newborn BALB/c mice is a known mouse model to study human infection. Here we evaluated transcriptional changes in the eye caused by blocking CXCR3 during MCMV infection.

ORGANISM(S): Mus musculus

PROVIDER: GSE271252 | GEO | 2024/11/20

REPOSITORIES: GEO

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Transcriptional profiling of eyes from MCMV infected neonatal mice during retinal development

Project description:Congenital CMV is the leading cause of congenital infections leading to several different neurological complications including ocular pathology. MCMV infeciton of newborn BALB/c mice is a known mouse model to study human infection. Here we evaluated transcriptional changes caused by the infection in the eye over the course of development from post natal day 5 to 28.

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Transcriptional analysis of ocular tissue from MCMV infected neonatal mice treated with CXCR3 blocking antibody

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