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Real-time quantitative PCR profiling of human miRNAs in CAG RNA-expressing cells

ABSTRACT: We examined whether PAPD5 upregulation induced by mutant CAG RNA led to any dysregulation of cellular miRNA profiling. We found that, out of the 751 miRNAs examined, the expression of 186 miRNAs was reduced in EGFPCAG78-expressing human neuroblastoma SK-N-MC cells and was restored back to normal levels upon the knockdown of PAPD5 expression.

ORGANISM(S): Homo sapiens

PROVIDER: GSE271666 | GEO | 2024/08/01

REPOSITORIES: GEO

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