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Systemic determination of PRDM16 regulatory genes in the aorta

ABSTRACT: We determined the differentially expressed genes in the thoracic aorta (TA) from vascular smooth muscle cell (VSMC)-specific Prdm16 knockout (Prdm16SMKO) and control mice by RNA-sequencing (RNA-seq) analysis. We also performed chromatin immunoprecipitation (ChIP)-sequencing (ChIP-seq) analysis to identify potential target genes of PRDM16. By overlapping the RNA-seq and ChIP-seq dataset, we are able to identify the target genes of PRDM16 in the aorta and investigate the roles of PRDM16 in the vascular biology.

ORGANISM(S): Mus musculus

PROVIDER: GSE272891 | GEO | 2025/01/15

REPOSITORIES: GEO

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