Transcriptomics

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Characterize the unique transcriptional changes in the embryonic trachea of knockout mice


ABSTRACT: To further identify the transcriptional changes underlying congenital tracheal malformation in a1H knockout mice, the differential gene expression panel was examined by Affymetrix microarray. To investigate the roles of a1H-regulated genes in tracheal development, we characterize the unique transcriptional changes of early trachea in kockout mice, and compare the expression profiles of knock out trachea with those of wild type trachea. We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up or down-regulated genes during this process.

ORGANISM(S): Mus musculus

PROVIDER: GSE27305 | GEO | 2014/02/14

SECONDARY ACCESSION(S): PRJNA137125

REPOSITORIES: GEO

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