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Expression data from Triple Negative Breast Cancer (TNBC) cell lines cultured in 2D and 3D.

ABSTRACT: Development of a reliable method for human triple-negative breast cancer organotypic culture: Improving imaging and genomic studies in 3D cultures The primary objectives of this study are to develop an advanced three-dimensional cell culture system to better model the tumor microenvironment in triple-negative breast cancer (TNBC), analyze the differences in molecular and cellular behavior between two-dimensional (2D) and 3D cultures, and investigate the impact of these differences on key oncogenic signaling pathways, specifically PI3K and β-catenin.

ORGANISM(S): Homo sapiens

PROVIDER: GSE277405 | GEO | 2024/09/20

REPOSITORIES: GEO

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Gene expression profiles of triple-negative breast cancer cells under the condition of 3D proliferation

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