Transcriptomics

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Exploring the Landscape of Microproteins in T Cells: Insights Gained from Nascent Protein Profiling and Global Proteomics Approaches


ABSTRACT: Microproteins, as hidden players in the proteomic club, are encoded by small open reading frames (sORFs) and have garnered increasing attention in recent years. T cells play a critical role in the immune system's response to cancer, however, the exploration of novel microproteins in T cells remains an unexplored area. In this study, we employed an integrated approach combined nascent protein profiling and quantitative global proteomics to identify novel microproteins in human T cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE277522 | GEO | 2024/09/24

REPOSITORIES: GEO

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