Salmonella infection accelerates potential maturation of the intestinal epithelium
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ABSTRACT: Postnatal establishment of enteric metabolic, host-microbial and immune homeostasis is the result of precisely timed and tightly regulated developmental and adaptive processes. Here, we show that infection with the invasive enteropathogen Salmonella Typhimurium results in a Myd88-dependent accelerated maturation of the neonatal epithelium with premature appearance of antimicrobial, metabolic, developmental, and regenerative features of the adult tissue.
ORGANISM(S): Mus musculus
PROVIDER: GSE278410 | GEO | 2024/12/17
REPOSITORIES: GEO
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