Transcriptome profiling of maize transcription factor mutants to probe gene regulatory network predictions

ABSTRACT: Loss-of-function mutant alleles were characterized for 22 maize transcription factors to test the functional relevance of prior yeast-one-hybrid and co-expression gene regulatory network predictions. The transcriptome and phenolic metabolome of these mutants were profiled to document the functional roles of these transcription factors. A subset of the prior gene regulatory network predictions were supported but had limited overall power in predicting changes in gene expression or phenolic compounds. The limitations of testing transcription factor-target predictions with single TF knockouts are discussed.

ORGANISM(S): Zea mays

PROVIDER: GSE280139 | GEO | 2024/10/23

REPOSITORIES: GEO