Transcriptomics

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The role of the ​​LysR-type transcription factor PacR in regulating nitrogen metabolism in Anabaena sp. PCC7120


ABSTRACT: Deletion of the global transcription factor PacR in Anabaena triggers heterocyst formation even in NO3- containing medium, likely due to impaired NO3- uptake and disrupted NH4+ assimilation in the GOGAT cycle. This phenotype may be exacerbated by reduced PSI-yield and reduced expression of ferredoxin, which may lead to less reducing equivalents for nitrogen uptake and fixation. These results highlight PacR’s role as a global regulator of carbon metabolism and photosynthesis while also establishing its involvement in regulating nitrogen metabolism.

ORGANISM(S): Nostoc sp. PCC 7120 = FACHB-418

PROVIDER: GSE280386 | GEO | 2024/11/05

REPOSITORIES: GEO

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