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3D hydrogel culture system for generation of fibrosis-associated macrophages

ABSTRACT: We identified a subpopulation of macrophages that are specifically enriched in interstitial lung disease. To better understand the functional relevance of this population with regards to disease pathogenesis by manipulating them in vitro, we attempted to induce this state in cell culture by prepurposing a published 3D hydrogel culture system originally designed to generate hematopoietic progenitor cells from PBMCs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE280632 | GEO | 2024/11/03

REPOSITORIES: GEO

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