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Transcriptomic signature associated with education in uterine Natural Killer cells during pregnancy

ABSTRACT: Uterine natural killer (uNK) cells regulate vascular changes crucial for placental function and fetal growth. The functional capacity of uNK cells is shaped by their education status. To explore the mechanisms of uNK cell education, we isolated NKG2A+ and Ly49C/I+ educated uNK cells and compared their transcriptomes to uneducated NKG2A-Ly49C/I- uNK cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE283336 | GEO | 2024/12/03

REPOSITORIES: GEO

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Human uterine Natural Killer cells regulate differentiation of extravillous trophoblast early in pregnancy - bulk RNA-seq data

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Transcriptomic signature associated with education in uterine Natural Killer cells during pregnancy

Project description:Transcriptomic signature associated with education in uterine Natural Killer cells during pregnancy

| PRJNA1193465 | ENA

Regulatory T cells promote decidual vascular remodeling by modulating uterine natural killer cells to support pregnancy in mice

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