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Transcription factor IRF4 deficiency in NK precursors pre-determines epigenetic changes in mature NK cells

ABSTRACT: To explore whether IRF4 deficiency determine the epigenetic changes of mature NK cells is at the NKP cell stage, ATAC-seq was performed to analyze chromatin accessibility of NK cells from spleen WT, Irf4-/-, Irf4flox/flox and Ncr1cre+/-Irf4flox/flox mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE283690 | GEO | 2024/12/11

REPOSITORIES: GEO

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Transcription factor IRF4 deficiency in NK precursors pre-determines epigenetic changes in mature NK cells

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