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Comparative analysis of the cardiomyocyte differentiation potential of induced pluripotent stem cells reprogrammed from human atrial or ventricular fibroblasts.

ABSTRACT: We generate Bulk-RNA sequencing data from two human-induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) cell lines. The first cell line was harvested 16 days after differentiation (hiPSC-CM-D16); this cell line still actively proliferated. The second cell line was harvested 140 days after differentiation (hiPSC-CM-D140); this cell line ceased proliferation. Comparing the Bulk-RNA sequencing data between these two cell lines may reveal regulators promoting hiPSC-CM proliferation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE289839 | GEO | 2025/02/18

REPOSITORIES: GEO

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Follistatin secreted by myocytes from hiPSCs results in cardiomyocyte cytokinesis in large mammal hearts with postinfarction LV remodeling

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