The Impact of HYOU1 Knockdown on Gene Expression in Hep3B Liver Cancer Cells
Ontology highlight
ABSTRACT: In order to explore the role of HYOU1 in liver cancer cells and identify its downstream target genes, we utilized lentiviral technology to knock down HYOU1 expression and established a stable HYOU1 knockdown Hep3B liver cancer cell line. Gene expression profiling was then performed using two groups of cells: the control group and the stable knockdown group (n=3).
Project description:WIPI2 regulates the growth of human liver cancer cells. We used microarray to detail the global program of gene expression underlying the cell growth of human liver cancer cell line Hep3b cells.