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Anti-CD3 mAb treatment reshapes infiltrating T and beta cells in the islets in autoimmune diabetes

ABSTRACT: Anti-CD3 mAb delays or prevents type 1 diabetes (T1D) by modulating the immune mediated destruction of beta cells. Our findings described the reshaping of islet-infiltrating T cells and beta cells that lead to operational, but tenuous tolerance to autoimmune diabetes following anti-CD3 mAb treatment.

ORGANISM(S): Mus musculus

PROVIDER: GSE292313 | GEO | 2025/03/24

REPOSITORIES: GEO

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Anti-CD3 mAb treatment reshapes infiltrating T and beta cells in the islets in autoimmune diabetes

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