Transcriptomics

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Effect of endoglin loss on embryoid bodies


ABSTRACT: Analysis of embryonic sten cell-derived embryoid bodies following endoglin knock out. Loss of endoglin leads to profound reduction of key hematopoietic regulators including SCL, LMO2, Gata2, and TGF-β signaling molecule ALK-1. Results provide insight into molecular mechanisms underlying hemangioblast and primitive hematopoietic development.

ORGANISM(S): Mus musculus

PROVIDER: GSE29300 | GEO | 2011/05/16

SECONDARY ACCESSION(S): PRJNA138629

REPOSITORIES: GEO

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